Curahan Hati Sesaat

lagi ngerjain pemicu 4b blok endokrin yg amit2 jibang2 ternyata ribet setengah mampus

kemaren ama tadi pagi ~ siang ngebaca faalna,, dah mayan oke tuh, uda mayan pede lha merasa kayanya penyakitna nda susa2 amat ni. begitu baca ttg penyakitna di herisen buju gile amit2. kenapa coba pada hiperaldosteronism primer, terjadi poliuri & polidipsi? nahlho kan harusna hiper aldosteron --> reabs Na meningkat, harusna urinna bukanna menurun? swt

terus kenapa nda terjadi edema? ini kata herisen:
Patients with primary aldosteronism characteristically do not have edema, since they exhibit an "escape" phenomenon from the sodium-retaining aspects of mineralocorticoids. Rarely, pretibial edema is present in patients with associated nephropathy and azotemia.

bzzzzzzzzz apaan tu escape2an
When normal individuals are given aldosterone, an initial period of sodium retention is followed by natriuresis, and sodium balance is reestablished after 3–5 days. As a result, edema does not develop. This process is referred to as the escape phenomenon, signifying an "escape" by the renal tubules from the sodium-retaining action of aldosterone. While renal hemodynamic factors may play a role in the escape, the level of atrial natriuretic peptide also increases. However, it is important to realize that there is no escape from the potassium-losing effects of mineralocorticoids

emang kenapa bisa escape si? ketakutan ngeliad aldosteron.. hohoho. berarti harusna dia pas awal2 kena hiperaldosteronism ga edema, tp ujung2na edema dung? apa yg nyebapin natrium escape?

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